A team of Australian and Indian researchers have published a landmark paper identifying the top 214 candidates for COVID-19 drug repurposing by methodically down-selecting from an initial list of 7,817.
The peer-reviewed paper “Systematic Down-Selection of Repurposed Drug Candidates for COVID-19” has been published by the International Journal of Molecular Sciences.
The paper has lead authors from BITS Pilani, one of the first institutions of eminence declared by the Indian government and Monash University, which has the world’s best pharmacy department according to the latest QS rankings.
Funded by $1.7 million by the Commonwealth’s Medical Research Future Fund and Australia’s science agency CSIRO, the study also involved Griffith, Melbourne, Queensland, Swinburne, Utah and York universities.
Senior author and University of York Professor S.S. Vasan who led the project, said, “It has been a massive team effort, going through nearly 8000 compounds and 14000 assay data, to down-select the top 200 methodically.“
“Without a single or two-dose COVID-19 vaccine that effectively stops infection, and with variants emerging continuously, we need to look at repurposed drugs for potential treatments that are safe, effective and affordable worldwide. However, it’s not feasible to look at thousands of candidates so our prioritisation methodology will be very useful,” he added.
The down-selection was conducted by a panel of experts co-chaired by Associate Professor Natalie Trevaskis of Monash University.
The Indian Sun acknowledges the support of the Victorian Government.
Support independent community journalism. Support The Indian Sun.
Follow The Indian Sun on Twitter | Instagram | Facebook
A team of Australian & Indian researchers have published a landmark paper identifying the top 214 candidates for #COVID19 #drug repurposing by methodically down-selecting from an initial list of 7,817. #TheIndianSun @indira_laisram https://t.co/22KmhlC64a
— The Indian Sun (@The_Indian_Sun) October 11, 2022
Indira @indira_laisram in conversation with Dr Prerna Varma, research fellow at Turner Institute for Brain & Mental Health. As someone researching #mentalhealth & the #pandemic, Varma talks about #sleep as an important factor in mental health. 😴
Full ▶️ https://t.co/caH1VGQ0hR pic.twitter.com/ov3FQHTlXp
— The Indian Sun (@The_Indian_Sun) October 10, 2022
Donate To The Indian Sun
Dear Reader,The Indian Sun is an independent organisation committed to community journalism. We have, through the years, been able to reach a wide audience especially with the growth of social media, where we also have a strong presence. With platforms such as YouTube videos, we have been able to engage in different forms of storytelling. However, the past few years, like many media organisations around the world, it has not been an easy path. We have a greater challenge. We believe community journalism is very important for a multicultural country like Australia. We’re not able to do everything, but we aim for some of the most interesting stories and journalism of quality. We call upon readers like you to support us and make any contribution. Do make a DONATION NOW so we can continue with the volume and quality journalism that we are able to practice.
Thank you for your support.
Best wishes,
Team The Indian Sun
